ATP mediates flow-induced NO production in thick ascending limbs
نویسندگان
چکیده
منابع مشابه
ATP mediates flow-induced NO production in thick ascending limbs.
Mechanical stimulation caused by increasing flow induces nucleotide release from many cells. Luminal flow and extracellular ATP stimulate production of nitric oxide (NO) in thick ascending limbs. However, the factors that mediate flow-induced NO production are unknown. We hypothesized that luminal flow stimulates thick ascending limb NO production via ATP. We measured NO in isolated, perfused r...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2012
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00504.2011